The BioInsights Podcast
Shear ignorance? Think again: breaking the perception of shear within viral vector manufacturing
November 09, 2022
Ratish Krishnan, Akshat Gupta
The tangential flow filtration (TFF) unit operation in viral vector manufacturing is a critical step on the path to commercialization. In this episode, Merck viral vector experts Ratish Krishnan and Akshat Gupta discuss best practices – and common misconceptions – when establishing process conditions and utilizing different TFF device formats.
How is TFF used in viral vector manufacturing?
What are the main types of TFF used in viral vector purification?
What are the key factors when it comes to designing a TFF step?
What are some common misconceptions regarding TFF?
How are your teams working to overcome negative perceptions?