The BioInsights Podcast

Navigating genomics and transcriptomics in the immuno-oncology space

March 01, 2024 BioInsights
The BioInsights Podcast
Navigating genomics and transcriptomics in the immuno-oncology space
Show Notes Chapter Markers

Lauren Coyle, Commissioning Editor, Immuno-Oncology Insights, interviews Katie Campbell, Postdoctoral Fellow, Cancer Research Institute, about her current research on genomics, transcriptomics, and spatial profiling to address challenges in the I-O field.

Can you tell us a bit about your career in the I-O space so far and what you're currently working on?
Looking at genomics and transcriptomics data, how has this successfully been implemented in I-O so far and what challenges remain to be solved?
How can these challenges be addressed going forward?
How does the integration of spatial profiling data contribute to a better understanding of molecular drivers and cellular interactions?
When it comes to navigating these questions, do you think it is better to start with a clear hypothesis or are there different routes that work better?
In your current research on somatic alterations and antigen-presenting machinery, how do you approach the analysis of HLA genes?
Following that, what strategies have you employed to identify and characterize copy number alterations in the antigen-presenting machinery?
How do you collaborate with experts from different fields, and how has this contributed to the progress of your research?
Finally, what are your main goals and aspirations for the future?