The BioInsights Podcast
The BioInsights Podcast: discussing the challenges of translating novel biologics from bench to clinic to market.
The BioInsights Podcast
Navigating genomics and transcriptomics in the immuno-oncology space
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BioInsights
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Season 3
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Episode 2
Lauren Coyle, Commissioning Editor, Immuno-Oncology Insights, interviews Katie Campbell, Postdoctoral Fellow, Cancer Research Institute, about her current research on genomics, transcriptomics, and spatial profiling to address challenges in the I-O field.
Can you tell us a bit about your career in the I-O space so far and what you're currently working on?
Looking at genomics and transcriptomics data, how has this successfully been implemented in I-O so far and what challenges remain to be solved?
How does the integration of spatial profiling data contribute to a better understanding of molecular drivers and cellular interactions?
When it comes to navigating these questions, do you think it is better to start with a clear hypothesis or are there different routes that work better?
In your current research on somatic alterations and antigen-presenting machinery, how do you approach the analysis of HLA genes?
Following that, what strategies have you employed to identify and characterize copy number alterations in the antigen-presenting machinery?
How do you collaborate with experts from different fields, and how has this contributed to the progress of your research?